Atazor R is used to treat HIV-1 infection as part of combination antiretroviral therapy. It helps reduce viral load and improve immunity.
Atazor R is used to treat HIV-1 infection as part of combination antiretroviral therapy. It helps reduce viral load and improve immunity.
What is Atazor R?
Atazor R is an antiretroviral medication used to treat HIV-1 infection.
It is a combination therapy containing:
Atazanavir (a Protease Inhibitor)
Ritonavir (a booster that increases the effectiveness of Atazanavir)
It is used as part of HAART (Highly Active Antiretroviral Therapy) in adults and adolescents.
Manufacturer
Atazor R is commonly manufactured by:
Emcure Pharmaceuticals Ltd.
Composition
Each tablet typically contains:
Atazanavir 300 mg
Ritonavir 100 mg
(Strengths may vary depending on the exact product variant.)
Working (Mechanism of Action)
Inhibits the HIV protease enzyme
Prevents new viral particles from maturing
Slows viral replication
Inhibits liver enzymes that metabolize Atazanavir
Boosts Atazanavir levels → makes it more effective
Together, they reduce viral load and increase CD4 counts.
How to Use Atazor R?
Take one tablet daily
Preferably with food (helps absorption)
Swallow whole with water
Take at the same time every day
Do not skip doses — it increases the risk of viral resistance.
Dosage
Typical adult dosage:
Atazor R (Atazanavir 300 mg + Ritonavir 100 mg)
Taken once daily with food, in combination with other antiretroviral medications (e.g., Tenofovir, Lamivudine).
Your HIV specialist determines the final regimen.
Warnings and Precautions
Liver disease or hepatitis
Kidney disease
Heart rhythm problems
High cholesterol
Hemophilia
Severe jaundice
Atazor R has many interactions. Avoid or check before use:
Proton pump inhibitors (e.g., omeprazole)
Antacids (take them 2 hours apart)
Rifampicin
Anti-arrhythmics
Anticoagulants
Anticonvulsants
Hormonal contraceptives
Cholesterol-lowering drugs
Herbal products like St. John’s Wort
Always discuss all medicines with your doctor.
Benefits
Reduces HIV viral load
Increases CD4 cell count
Slows progression to AIDS
Improves immunity
Well-studied, effective once-daily regimen
Ritonavir boosting improves drug levels for better control
Avoid Taking Atazor R
You are allergic to Atazanavir or Ritonavir
You take medications that cause dangerous interactions
You have severe liver impairment
You are taking contraindicated acid-reducing drugs
You use recreational drugs or heavy alcohol
Side Effects
Jaundice (yellow eyes/skin)
Nausea
Stomach pain
Diarrhea
Rash
Fatigue
Changes in body fat distribution
Kidney stones
High bilirubin levels
Increased cholesterol
Peripheral neuropathy
Severe allergic reaction
Irregular heartbeat
Unusual bleeding
Severe abdominal pain
Dark urine / pale stools
Pancreatitis
Where to Store
Store below 25°C
Keep in a dry place
Protect from light and moisture
Keep out of reach of children
Keep tablets in the original container to avoid moisture damage
Conclusion
Atazor R is a powerful HIV antiretroviral combination therapy containing Atazanavir and Ritonavir. It effectively reduces viral load and boosts immunity when taken consistently with food.
Regular monitoring, adherence, and medical supervision are essential due to multiple potential interactions and side effects.
FAQS
Atazor R is used to treat HIV-1 infection as part of combination antiretroviral therapy. It helps reduce viral load and improve immunity.
Each tablet contains:
Atazanavir 300 mg
Ritonavir 100 mg
Ritonavir boosts the effect of Atazanavir.
Take one tablet once daily
Always with food
Swallow whole with water
Taking it without food reduces absorption and effectiveness.
Take it as soon as you remember
If it’s almost time for the next dose, skip the missed dose
Do not double-dose
Missing doses increases the risk of drug resistance.
No. HIV treatment must be taken long-term and exactly as prescribed. Stopping may lead to viral resistance and serious health complications.
Common reactions include:
Yellowing of eyes/skin (high bilirubin)
Nausea, vomiting
Headache
Abdominal pain
Rash
Diarrhea
Tiredness
Yellowing is usually harmless but should be monitored.
It can cause increased bilirubin, leading to yellow eyes/skin.
This is usually cosmetic and not harmful, but severe or worsening jaundice should be reported.
Use with caution.
Take antacids 2 hours before or after Atazor R
Avoid proton pump inhibitors (like omeprazole or pantoprazole) unless approved by your doctor
These medicines reduce Atazor R absorption.