Cyclophil Me 25 mg Capsule is an immunosuppressant medicine that contains Cyclosporine as its active ingredient.
Cyclophosphamide Me 25 is primarily used to prevent organ rejection after transplantation (such as a kidney, liver, or heart transplant) and to treat certain autoimmune diseases like rheumatoid arthritis, psoriasis, and nephrotic syndrome.
Cyclophil Me 25mg is a brand name for cyclosporine, a prescription immunosuppressant medication. It belongs to a class of drugs called calcineurin inhibitors.
Key Details
| Particulars | Description |
|---|---|
| Brand Name | Cyclophil Me 25 mg |
| Manufacturer | Biocon Ltd. |
| Active Ingredient | Cyclosporine 25 mg |
| Drug Class | Immunosuppressant |
| Dosage Form | Soft Gelatin Capsule |
How Cyclophil Me Works
Cyclosporine inhibits the immune system’s T-cells by blocking calcineurin, a protein involved in immune response activation. This reduces inflammation and prevents the body from attacking its own tissues.
Cyclophil Me 25 (Cyclosporine) works by suppressing the immune system.
Normally, your immune system attacks foreign substances — including a transplanted organ.
Cyclosporine reduces the activity of certain immune cells (T-lymphocytes), preventing organ rejection and controlling autoimmune inflammation.
Common Uses
Autoimmune disorders, Such as rheumatoid arthritis, psoriasis, and psoriatic arthritis to reduce joint inflammation and skin symptoms.
Organ transplant: To prevent rejection in kidney, liver, or heart transplants.
Other conditions: Off-label for conditions like atopic dermatitis, ulcerative colitis, or nephrotic syndrome. It’s typically used when other treatments fail and requires close monitoring due to its immunosuppressive effects.
👇 Main Actions:
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Prevents organ rejection in transplant patients
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Reduces inflammation in autoimmune diseases
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Helps preserve kidney function in nephrotic syndrome
Uses of Cyclophil Me 25 mg
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Prevention of organ transplant rejection
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Kidney, heart, liver, or bone marrow transplants
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Autoimmune diseases
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Psoriasis
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Atopic dermatitis (severe eczema)
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Nephrotic syndrome (kidney condition)
Dosage & Administration
| Condition | Typical Dose | Administration |
|---|---|---|
| Organ transplant (prevention) | Does individualized (by weight & blood levels) | Orally, once or twice daily |
| Rheumatoid arthritis / Psoriasis | Usually 2.5–5 mg/kg/day | Adjusted as per the response |
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Take the capsule at the same time daily, with or without food.
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Swallow whole; do not crush or chew.
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The dose is adjusted based on blood levels of cyclosporine to maintain effectiveness and reduce toxicity.
⚠️ Always follow your doctor’s exact dosing schedule — self-adjustment can be harmful.
Possible Side Effects
Common:
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Headache, nausea
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Tremors or shaking
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Increased hair growth (hypertrichosis)
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Gum swelling or tenderness
Serious:
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Kidney or liver dysfunction
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High potassium levels
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Seizures or confusion (rare)
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Increased susceptibility to infections
Contact your doctor immediately if you notice decreased urine output, persistent nausea, or yellowing of eyes care/skin.
Precautions
| Condition | Advice |
|---|---|
| Pregnancy / Breastfeeding | Use only if clearly needed under medical supervision |
| Kidney / Liver disease | Use cautiously — requires close monitoring |
| Hypertension | Regular blood pressure checks are recommended |
| Immunosuppression | Avoid exposure to infection or live vaccines |
⚠️ Monitoring Required:
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Kidney & liver function tests
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Blood pressure
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Blood cyclosporine levels
Drug Interactions
Avoid or use with caution when combined with:
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NSAIDs (e.g., ibuprofen, naproxen)
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Antibiotics/antifungals (erythromycin, ketoconazole)
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Anti-seizure drugs (phenytoin, carbamazepine)
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St. John’s Wort (herbal supplement)
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Grapefruit juice (increases drug levels dangerously)
Storage
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Store below 25°C
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Keep away from moisture and sunlight
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Store in the original blister pack
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Keep out of reach of children
Key Takeaway
Cyclophil Me 25 mg (Cyclosporine) is a potent immunosuppressant that helps prevent organ rejection and manage autoimmune diseases.
It must be used under strict medical supervision with regular monitoring to avoid serious side effects and ensure proper immune control.
