LOX 2% — Overview
LOX 2% is a local anesthetic medication that contains Lidocaine Hydrochloride 2% as its active ingredient.
It is used to numb (anesthetize) a specific area of the body during minor surgical or dental procedures, or to relieve pain and discomfort from skin or mucous membrane irritation.
Lox 2% refers to luliconazole 2% cream, a topical antifungal medication used to treat superficial fungal infections of the skin, particularly those caused by dermatophytes and yeasts. It’s a newer azole antifungal, effective for conditions like athlete’s foot and jock itch.
Manufacturer
Commonly marketed by Neon Laboratories Ltd., Neon Pharma, or Neon Laboratories Pvt. Ltd.
Drug Class
Local Anesthetic
Active Ingredient
Lidocaine Hydrochloride 2% w/v
Key Facts and Mechanism
Active Ingredient: Luliconazole 2% w/w.
How It Works: Inhibits ergosterol synthesis in fungal cell membranes by blocking lanosterol 14α-demethylase, leading to fungal cell death. It’s broad-spectrum against dermatophytes, yeasts, and some molds.
Indications: Tinea infections (e.g., tinea pedis, tinea cruris, tinea corporis); also for pityriasis versicolor and cutaneous candidiasis. Not for nail infections.
Dosage: Apply thinly to the affected area once daily for 2 weeks (up to 4 weeks for severe cases); wash hands after use.
How LOX 2% Works
LOX (Lidocaine) works by:
-
Blocking sodium channels in nerve cells,
-
This prevents nerve impulses from transmitting pain signals to the brain.
⚡ This causes temporary loss of sensation or numbness in the treated area.
Common Forms & Uses
| Form | Typical Use |
|---|---|
| LOX 2% Jelly | Applied topically to mucous membranes (mouth, nose, throat, or genitals) for pain relief before procedures |
| LOX 2% Gel | Used for minor burns, skin irritation, insect bites, or hemorrhoids |
| LOX 2% Injection | Used by doctors for local anesthesia during minor surgeries, suturing, dental work, or nerve blocks |
Medical Uses Include:
-
Minor dental procedures
-
Endoscopy, cystoscopy, or catheter insertion
-
Intubation (to reduce throat discomfort)
-
Relief from mouth ulcers or sore gums
-
Pain from burns, cuts, or insect bites
-
Anal fissures or hemorrhoid pain relief
Dosage & Administration
-
Topical (gel/jelly): Apply a thin layer 2–3 times a day on the affected area.
-
Injection: Administered only by a doctor or trained medical professional.
-
Do not exceed the recommended dose — excessive use can cause systemic toxicity.
⚠️ Always follow your doctor’s instructions for dosage and duration.
Side Effects
Usually mild and temporary:
-
Local redness or irritation
-
Burning or itching at the application site
-
Numbness beyond the target area (if overused)
Serious (rare):
-
Blurred vision
-
Slow heart rate or breathing difficulty (from overdose or injection mishandling)
If any severe reaction occurs, seek medical help immediately.
Precautions
| Condition | Advice |
|---|---|
| Pregnancy / Breastfeeding | Generally safe in small amounts, but consult your doctor |
| Heart, liver, or kidney disease | Use cautiously |
| Allergy to Lidocaine or other anesthetics | Avoid use |
| Children | Use under medical supervision only |
Avoid contact with eyes or deep wounds unless advised by a doctor.
Drug Interactions
Inform your doctor if you are using:
-
Antiarrhythmics (e.g., Amiodarone, Mexiletine)
-
Beta-blockers
-
Other local anesthetics
Storage
Store below 25°C
Keep in a cool, dry place away from sunlight
Do not freeze
Keep out of children’s reach
Key Takeaway
LOX 2% (Lidocaine Hydrochloride) is a fast-acting local anesthetic that provides temporary numbness and pain relief for medical or dental procedures and minor skin care conditions.
Safe when used correctly — but should always be applied or administered under medical guidance.
