Tretiva 10 Mg Soft Capsule – Overview
Tretiva 10 mg is a retinoid medication used to treat severe acne (nodular or cystic acne) that does not respond to other treatments such as antibiotics or topical creams.
It contains Isotretinoin, a derivative of Vitamin A, which effectively reduces oil (sebum) production, prevents clogged pores, and promotes skin renewal.
Tretiva 10 mg Capsule is a vitamin A derivative (retinoid) used to treat severe acne (nodular or cystic acne) that does not respond to other treatments like antibiotics or topical creams.
Tretiva 10 Mg Soft Capsule contains Isotretinoin, which is highly effective in reducing oil (sebum) production, unclogging pores, and preventing acne formation.
Key Details
| Particulars | Description |
|---|---|
| Brand Name | Tretiva 10 mg Capsule |
| Manufacturer | Intas Pharmaceuticals Ltd. |
| Active Ingredient | Isotretinoin 10 mg |
| Drug Class | Retinoid / Anti-acne medicine |
| Form | Soft Gelatin Capsule |
How Tretiva Works
Isotretinoin works by reducing the production of sebum (oil) in the skin, which helps unclog pores and prevent acne formation. It also has anti-inflammatory effects and promotes skin cell turnover.
Clinical studies (e.g., published in The Journal of the American Academy of Dermatology) show it significantly reduces acne lesions in 80-90% of patients, often leading to long-term remission. It targets the root causes of acne rather than just symptoms.
Tretiva (Isotretinoin) acts by:
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Decreasing sebum (oil) production in the skin’s sebaceous glands.
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Preventing clogging of pores that leads to pimples.
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Reducing bacterial growth and inflammation.
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Helping skin regenerate and heal faster.
🧴 Tretiva 10 Mg Soft Capsule treats acne from the root cause, not just the symptoms.
Common Uses
Severe acne: For nodular or cystic acne that hasn’t responded to antibiotics, topical treatments, or other therapies.
Off-label uses: Sometimes prescribed for conditions like rosacea or certain skin disorders, but this should be under medical supervision.
It’s not for mild acne or as a first-line treatment. It’s often used when acne causes scarring or significant psychological distress.
Dosage Information
| Condition | Typical Dose | Duration |
|---|---|---|
| Severe acne (nodular/cystic) | 10–40 mg daily | 15–20 weeks (as prescribed) |
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The dosage depends on body weight and response to treatment.
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Usually started at 0.5 mg/kg per day and adjusted gradually.
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Take with food to improve absorption.
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Swallow whole — do not crush or chew.
⚠️ Do not stop or change the dose without consulting your dermatologist.
How to Take Tretiva 10 mg
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Take the capsule once or twice daily, as directed by your doctor.
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Always take it with meals — fat helps absorb isotretinoin.
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Use a moisturizer and lip balm regularly, as dryness is common.
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Continue the full course even if acne improves early.
Side Effects
Common (mild and reversible):
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Dry lips, mouth, or eyes
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Skin peeling or itching
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Nosebleeds
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Sensitivity to sunlight
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Mild muscle or joint pain
Serious (consult your doctor immediately):
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Vision or hearing problems
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Mood changes (depression, irritability)
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Severe abdominal pain or diarrhea
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Persistent headache or dizziness
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Signs of liver issues (yellow skin/eyes)
Precautions
| Condition | Advice |
|---|---|
| Pregnancy | 🚫 Strictly contraindicated (can cause severe birth defects) |
| Breastfeeding | Avoid use |
| Blood donation | Avoid during and for 1 month after stopping treatment |
| Liver disease / high cholesterol | Use with caution |
| Contraception | Use two reliable birth control methods before, during, and after treatment |
⚠️ Women of childbearing age must have a negative pregnancy test before starting and monthly during therapy.
Drug Interactions
Avoid combining with:
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Vitamin A supplements (risk of toxicity)
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Tetracycline antibiotics
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Alcohol (may worsen liver strain)
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Other acne medications (benzoyl peroxide, retinoids) without medical advice
Storage
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Store below 25°C
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Keep away from sunlight and moisture
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Out of reach of children
Key Takeaway
Tretiva 10 mg (Isotretinoin) is a powerful oral acne medication that targets acne at its source by reducing oil production and preventing pore blockages.
It offers long-term, often permanent results — but must be used under strict medical supervision, especially for women.

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