What Is Wormentel 150 mg?
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Active Ingredient: Fenbendazole.
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Strength: 150 mg per tablet.
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Manufacturer: Kachhela Medex Pvt. Ltd.
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Pharmacological Class: It’s a benzimidazole anthelmintic (i.e., a broad-spectrum dewormer).
Mechanism of Action
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Fenbendazole works by binding to β-tubulin in parasite cells, which disrupts microtubule formation, messing up how parasites absorb nutrients.
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This prevents them from taking up glucose and producing energy, causing them to die or be expelled.
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According to regulatory data, it is metabolized slowly; much is excreted via feces, and the unchanged or metabolized drug is eliminated primarily that way.
What Is Wormentel 150 Used For?
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Veterinary Use: Primarily used in animals (e.g., dogs, cats, livestock) to treat a variety of parasitic worm infections: roundworms, hookworms, whipworms, and some tapeworms.
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Parasitic Control: Effective for internal parasites (nematodes) and often used in routine deworming protocols.
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Off-Label / Experimental: Some sources mention fenbendazole being explored (or used off-label) in humans for cancer, but this is not a confirmed or approved standard treatment.
Dosage & Administration
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For animals, the dosage depends on species and weight.
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For example, in some veterinary references, ~5 mg/kg is recommended for certain animals.
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Administration is oral, typically with food to reduce stomach upset.
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Duration may be 3–5 daysdependingg on the infection.
Side Effects & Safety Profile
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Generally well-tolerated in animals.
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Possible side effects: nausea, diarrhea, lethargy.
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In higher or prolonged doses (in animal studies), some toxic effects have been seen (e.g., lymphoid changes, some neurological effects in very high doses).
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According to toxicology data, the acute toxicity is low.
Precautions / Warnings
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Veterinary Use Only: Primarily indicated for animals.
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Use with caution in animals with liver problems, because of metabolism concerns.
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Pregnancy / Breeding Animals: Use only under vet supervision.
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Storage: Store in a cool, dry place, protected from light.
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Human Use: Not officially approved for humans by major regulatory bodies (e.g., EMA, FDA).
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Toxicity in Humans: Very limited data on safety, and use in humans is largely experimental/off-label.
Regulatory / Toxicology Data
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According to European regulatory assessment, fenbendazole has low acute toxicity in animal studies.
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In repeat-dose studies in animals, very high doses caused some adverse effects in the liver and lymph nodes.
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Oral bioavailability is limited, and much of the drug is excreted via feces.
Bottom Line
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Wormentel 150 is a veterinary dewormer, not primarily intended for humans.
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It’s effective against a broad spectrum of intestinal parasites in animals.
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While there is some interest in off-label human use (especially in “alternative cancer” contexts), this is not clinically established or approved.
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Use should be guided by a veterinarian (for animals) or a medical professional (if someone is considering it for non-approved use).
