What Is Xovoltib 50 mg?
The active ingredient is Afatinib dimaleate.
Xovoltib 50 is marketed by Boehringer Ingelheim.
Therapeutic class: Tyrosine Kinase Inhibitor (TKI)/anti-cancer.
Used for non-small cell lung cancer (NSCLC) in patients with certain EGFR (epidermal growth factor receptor) mutations.
How It Works
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Afatinib (Xovoltib) blocks several EGFR receptors (ErbB1, ErbB2/HER2, ErbB3, ErbB4) on cancer cells.
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By inhibiting these, it interferes with the signaling that promotes cancer cell growth and survival.
How to Use Xovoltib 50
Dosage: As prescribed by your doctor. Commonly 50 mg daily for some forms of NSCLC.
Administration: Take Xovoltib 50 on an empty stomach. According to 1mg, preferably “at least 1 hour before a meal or 3 hours after” a meal.
Swallow whole: Don’t chew or crush the tablet.
Consistency: Try to take it at the same time every day.
Common Side Effects
Some of the common side effects include:
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Skin rash.
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Dry skin.
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Nausea / Vomiting.
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Loss of appetite.
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Itching.
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Mouth inflammation/sores (stomatitis).
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Nail disorders/infections.
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Other: dry eyes, runny nose, peeling / pain in hands-feet skin.
Less common or serious ones:
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Pancreas inflammation (rare).
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Severe skin reactions (rare).
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Breathing issues/lung inflammation.
Precautions & Warnings
Tell your doctor if you have lung problems, liver issues, kidney problems, or heart disease before starting.
Pregnancy / Breastfeeding: Not recommended.
Sun sensitivity: This drug can make your skin more sensitive to sunlight. Use sunscreen, protective clothes.
Alcohol: Use caution. Some sources say to avoid or limit.
Interactions: Important to tell your doctor about all other meds — there are potential interactions.
Monitoring: Your doctor may ask for blood tests to monitor side effects.
Fertility: May reduce fertility in men and women. Talk to your doctor about sperm/egg preservation if needed.
What to Do If Side Effects Appear
Diarrhea: Stay well hydrated; your doctor may prescribe an anti-diarrheal (like loperamide) if needed.
Rash / Skin Reactions: Use gentle skin care, avoid harsh sun exposure, and inform your doctor if severe.
Eye Symptoms: If there’s pain or redness in the eyes, or very dry eyes, let your oncologist know.
Missed Dose: If you miss a dose, take it as soon as you remember unless it’s almost time for the next dose. Don’t double up.
Overdose / Severe Reaction: Seek medical help immediately.
Effectiveness
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This is not a cure for cancer in most cases, but a targeted therapy: it can slow down tumor growth, reduce tumor size, and improve survival / quality of life.
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The effect may take weeks to months to become noticeable.
Bottom Line
Xovoltib 50 mg is a powerful targeted cancer drug (Afatinib) for EGFR-mutated non-small cell lung cancer.
It requires strict medical supervision, regular monitoring, and good adherence to how and when you take it.
Side effects are common but manageable — talk to your doctor immediately about any you experience.
Don’t start or stop this medicine on your own.






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